PANDAS (pediatric autoimmune neuropsychiatric disorders associated with streptococcal infections) occurs in predisposed children when the immune system responds to an infection like strep throat by attacking the brain. The resulting inflammation can lead to sudden-onset symptoms such as violent body tics and obsessive-compulsive activity. Finding the cause of PANDAS is key to treatment. Because the condition is unique to each person, it takes time and patience to peel the layers and analyze the complex symptoms. But with the right therapies, children can work toward getting back to their happy selves.